Potassium
| Potassium | |
|---|---|
| Chemical formula | K (element); biological form mainly K⁺ |
| Solubility | Potassium salts are water-soluble; chloride and citrate are common forms |
| Bioavailability | Nearly complete absorption; renal excretion adjusts balance; diuretics and low magnesium increase loss |
| Dietary sources | Fruits, potatoes, milk, broth, coconut water; orange juice is high in potassium and vitamin C |
| RDA (adults 19–50 y) | ~2,600–3,400 mg/day (US adult adequate intake) |
| Upper limit | No established UL for food potassium; supplements require caution in kidney disease |
Potassium (K⁺) is the main intracellular cation, paired with Magnesium, while Sodium and Calcium dominate extracellular fluid when metabolism is efficient.[1]
Stressed or de-energized cells lose magnesium and potassium and absorb sodium and calcium in his calcium article.[2] Hypothyroidism and inflammation shift that balance.[3]
History
[edit]Etymology
[edit]The English name comes from "potash" (ashes leached in a pot, a traditional source of potassium carbonate). The chemical symbol K comes from Latin kalium, itself from Arabic al-qaly ("the ashes").
Humphry Davy isolated potassium in 1807 by electrolysis of molten potash, the first metal isolated by electrolysis.
Structure/Chemical properties
[edit]Potassium (atomic number 19) sets resting membrane potential with sodium. Mainstream physiology treats serum potassium as a critical electrolyte for heart rhythm and nerve conduction.
Function/Mechanism of Action
[edit]Insulin itself has been found to account for only about 8% of the "insulin-like activity" of the blood, with potassium being probably the largest factor.
— Ray Peat
Peat used blood glucose and sodium concentration to modulate inflammatory reactivity in MS writing: high glucose made even strong antigens mildly irritating, while very low glucose made mild irritants deadly; varying sodium had a weaker parallel effect.[5] Serum potassium appears among useful thyroid-context labs in his hypothyroidism article.[6]
Potassium citrate supports bone mineral balance in epidemiology Peat cited on the calcium page.[7][8]
Medical uses/Effects
[edit]Mainstream medicine uses potassium chloride for deficiency and potassium citrate for some kidney stones. Peat's dietary emphasis is fruit-and-milk patterns with adequate minerals rather than isolated potassium megadoses.[9] Pair with Magnesium, Thyroid, and Glucose stability in his MS and hypothyroidism themes.[10]
A meta-analysis of 22 randomized controlled trials found increased potassium intake lowered systolic blood pressure by about 3.5 mmHg and diastolic by about 2 mmHg in adults, with a larger effect in people with existing hypertension and no adverse effect on blood lipids, catecholamines, or kidney function.[11] This lines up with Peat's fruit-forward, potassium-rich dietary pattern rather than isolated high-dose supplementation, which carries hyperkalemia risk in kidney disease.
Side/Adverse effects
[edit]Hyperkalemia from supplements or renal failure causes arrhythmia. Hypokalemia follows diuretics, vomiting, and aldosterone excess. Low Magnesium worsens potassium loss in standard clinical teaching.
Dosing
[edit]No fixed supplement dose given. Orange juice supplies potassium and vitamin C; Peat warned against pairing high vitamin C drinks with iron-heavy meals when limiting iron uptake.[12] See Harm reduction.
References
[edit]- ↑ "Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy," Ray Peat article
- ↑ "Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy," Ray Peat article
- ↑ "Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy," Ray Peat article
- ↑ "Glycemia, starch, and sugar in context," Ray Peat article
- ↑ "Multiple sclerosis, protein, fats, and progesterone," Ray Peat article
- ↑ "TSH, temperature, pulse rate, and other indicators in hypothyroidism," Ray Peat article
- ↑ "Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy," Ray Peat article
- ↑ Jehle S, Hulter HN, Krapf R, "Effect of potassium citrate on bone density, microarchitecture, and fracture risk in healthy older adults without osteoporosis: a randomized controlled trial," Journal of Clinical Endocrinology & Metabolism. 2013;98(1):207-17. doi:10.1210/jc.2012-3099. PMID 23162100.
- ↑ "Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy," Ray Peat article
- ↑ "Multiple sclerosis, protein, fats, and progesterone," Ray Peat article
- ↑ Aburto NJ, Hanson S, Gutierrez H, Hooper L, Elliott P, Cappuccio FP. "Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses," BMJ. 2013;346:f1378. doi:10.1136/bmj.f1378. PMID 23558164.
- ↑ "Iron's Dangers," Ray Peat article