Folic acid
Folic acid is the synthetic folate used in fortified foods and many supplements. Folate is the broader vitamin B9 family.
Peat's view
[edit]Pregnancy care uses folate for neural tube prevention under medical guidance. Food folates appear in liver and greens. High synthetic doses are a clinical topic, not a casual stack.
Suicide risk research
[edit]A pharmacoepidemiologic study of 866,586 privately insured US adults found that months covered by an active folic acid prescription carried a 44% lower rate of suicide attempts and intentional self-harm than uncovered months (adjusted hazard ratio 0.56, 95% CI 0.48-0.65). The dose involved was prescription-strength folic acid (typically 1 mg/day), not the smaller amounts in fortified flour or a multivitamin.[1] This is a claims-database association, not a controlled trial of folic acid itself, and does not resolve the food-folate-versus-synthetic-folic-acid question above.
See also
[edit]References
[edit]- ↑ Gibbons RD, Hur K, Lavigne JE, Mann JJ. Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults. JAMA Psychiatry. 2022;79(12):1218-1226. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2796907